Dotfix 1mg Tablet | Dotinurad
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Home Medicines Gout Dotfix 1mg Tablet 1 Strip

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Dotfix 1mg Tablet 1 Strip

Generic: Dotinurad

Type: Tablet

Pack Size: 10 Pcs

Dotfix 1 is indicated for:
✔️ Gout management – Helps prevent and treat flare-ups.
✔️ Hyperuricemia treatment – Reduces uric acid levels in the blood.

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Discount Price: ৳ 116
MRP: ৳ 120 3% Off

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  • Cash on Delivery - All over Bangladesh
  • Regular Delivery - 8-12 Hours, Dhaka City*
  • Regular Delivery - 24-48 Hours, All Over Bangladesh*

✅ Description:

Dotfix 1 is an effective selective urate reabsorption inhibitor designed to reduce uric acid levels and prevent gout attacks. However, patients must adhere to proper dosage adjustments and precautions to minimize risks and side effects. Regular monitoring, especially for kidney and liver function, is crucial for safe use. Always consult your doctor before making changes to your treatment regimen.

Effectively lowers uric acid levels
Selective inhibition for fewer side effects
Monitored dosage adjustments for optimal safety

💙 For a healthier, gout-free life, consult your doctor before starting Dotfix 1

Safety Advices


Alcohol
UNSAFE
  • Caution is advised when consuming alcohol while taking Dotfix 1. Consult your doctor for guidance.

Pregnancy
CONSULT YOUR DOCTOR

Should only be used if the benefits outweigh the risks. Consult your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

The drug is excreted in breast milk. Consult your doctor before breastfeeding.


Driving
CAUTION

It is unknown whether Dotfix 1 affects driving ability. Do not drive if you experience dizziness, drowsiness, or difficulty concentrating.


CONSULT YOUR DOCTOR
  • Dotfix 1 acts in the renal proximal tubule, and its effectiveness depends on kidney function.
  • Alternative treatments should be considered for patients with severe renal impairment.
  • Avoid use in patients with oliguria (low urine output) or anuria (no urine output).

CONSULT YOUR DOCTOR

Patients should undergo regular liver function tests, as serious liver damage has been observed with some other uricosuric drug

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✔️ Pharmacology

Dotinurad, the active ingredient in Dotfix 1, selectively inhibits URAT1, preventing the reabsorption of uric acid in the kidneys. This leads to increased uric acid excretion, thereby lowering serum uric acid levels. Unlike some other urate-lowering drugs, Dotfix 1 has minimal impact on other uric acid transporters like ABCG2, OAT1, and OAT3, making it highly selective and efficient.

✔️ Dosage & Administration

💊 Adults:

  • Initial dose: 0.5 mg once daily.
  • After 2 weeks: Increase to 1 mg daily.
  • After 6 weeks: Increase to 2 mg daily (maintenance dose).
  • Maximum dose: 4 mg per day.

💊 Children:

  • Not recommended.

💊 Renal Impairment:

  • Efficacy may be reduced in patients with renal dysfunction.
  • Avoid use in patients with oliguria or anuria due to lack of expected effectiveness.
✔️ Potential Side Effects

🔹 Common side effects (1%–5% occurrence):

  • Gouty arthritis flare-ups
  • Limb discomfort

🔹 Rare side effects (<1% occurrence):

  • Loose stools
  • Increased gamma-glutamyl transferase (γ-GTP)
  • Joint pain (arthralgia)
  • Kidney stones (nephrolithiasis)
  • Calcium deposits in kidneys (nephrocalcinosis)
  • Elevated urinary β2-microglobulin levels
  • Increased blood creatinine levels
  • Elevated urine albumin/creatinine ratio
  • Presence of urine albumin

Note: If severe side effects occur, consult your doctor immediately.

✔️ Missed Dose:
  • Take the missed dose as soon as you remember.
  • If it’s close to the next scheduled dose, skip the missed one.
  • Never double the dose.
✔️ Important Considerations
  • Gout attacks may initially worsen when starting urate-lowering therapy due to a rapid drop in uric acid levels.
  • If a gout flare-up occurs before starting Dotfix 1, wait until symptoms subside before initiating treatment.
  • If a gout attack occurs during treatment, continue taking Dotfix 1 at the same dose. Additional medications (e.g., colchicine, NSAIDs, or corticosteroids) may be needed for symptom management.
✔️ Drug Interactions

⚠️ Medications that may reduce the effectiveness of Dotfix 1:
 

1️⃣ Pyrazinamide (Anti-TB drug):

  • May suppress uric acid excretion, potentially weakening the effect of Dotfix 1.

2️⃣ Salicylates (Aspirin & related drugs):

  • These medications may counteract the uric acid-lowering effects of Dotfix 1 by reducing uric acid excretion.

💡 Consult your doctor before using Dotfix 1 with these medicationsgs.

Frequently Asked Questions (FAQs) ❓

🛒 Orders

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+ Q. Can I cancel my order?

Yes, you can cancel your order before it is shipped. Contact customer support for assistance.

📦 Delivery

+ Q. What is the delivery time?

Delivery typically takes 1-2 business days, depending on your location.

+ Q. Does ePharma deliver internationally?

Currently, ePharma only delivers within Bangladesh.

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+ Q. What payment methods are accepted?

We accept debit/credit cards, Bkash, Nagad, and cash on delivery.

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Yes, all medicines are sourced from licensed pharmaceutical companies.

+ Q. Can I buy over-the-counter medication?

Yes, you can purchase over-the-counter medication on ePharma.

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+ Q. Can I return or exchange products?

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Check our pricing section for Dotfix 1mg Tablet 1 Strip price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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